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Download the "Solution Pharmacy" Mobile App to Get All Uploaded Notes, Model Question Papers, Answer Papers, Online Tests and other GPAT Materials - https://play.google.com/store/apps/de... Contents for 2nd Unit of Inorganic Chemistry - (01) Acids, Bases and Buffers: Buffer equations and buffer capacity in general, buffers in pharmaceutical systems, preparation, stability, buffered isotonic solutions, measurements of tonicity, calculations and methods of adjusting is tonicity. (02) Major extra and intracellular electrolytes: Functions of major physiological ions, Electrolytes used in the replacement therapy: Sodium chloride*, Potassium chloride, Calcium gluconate* and Oral Rehydration Salt (ORS), Physiological acid-base balance. (03) Dental products: Dentifrices, the role of fluoride in the treatment of dentalcare, Desensitizing agents, Calcium carbonate, Sodium fluoride, and Zinc eugenol cement. Dental Products = Dentifrices & Role of Fluoride in Dental Care Products Dentifrices Dentifrices are preparations meant to clean the teeth and other parts of oral cavity (gums) using a finger or a toothbrush. They are available as tooth powder, toothpaste, gels, dental creams, and even as dental foams. Dentifrices serve multiple functions in oral hygiene through the inclusion of a variety of agents. They act as plaque- and stain-removing agents through the use of abrasives and surfactants. Pleasant flavors and colors encourage their use. Fluoride is a mineral in your bones and teeth. It’s also found naturally in the water, soil, plants, rocks, air. Fluoride is commonly used in dentistry to strengthen enamel, which is the outer layer of your teeth. Fluoride helps to prevent cavities. It’s also added in small amounts to public water supplies in the United States and in many other countries. This process is called water fluoridation. In the context of human health, fluoride is mainly used to improve dental health. You can sometimes find it in your local water supply and in many over-the-counter (OTC) products, including: 1. Toothpaste 2. Mouth rinses 3. Supplements Fluoride is beneficial to teeth because it helps to: 1. Rebuild (remineralize) weakened tooth enamel slow down the loss of minerals from tooth enamel reverse early signs of tooth decay. 2. Prevent the growth of harmful oral bacteria 3. When bacteria in your mouth break down sugar and carbs, they produce acids that eat away at the minerals in your tooth enamel. This loss of minerals is called demineralization. Weakened tooth enamel leaves your teeth vulnerable to bacteria that cause cavities. Fluoride helps to remineralize your tooth enamel, which can prevent cavities and reverse early signs of tooth decay. Fluoride prevents tooth decay by making the enamel more resistant to the action of acids. They and accelerate the buildup of healthy minerals in the enamel, further slowing the occurrence of decay. Studies even show that in some cases, fluoride can stop already-started teeth decay. Dentifrices, including toothpowder and toothpaste, are agents used along with a toothbrush to clean and polish natural teeth. They are supplied in paste, powder, gel, or liquid form. Sodium fluoride (NaF) is a fluoride salt commonly used in dentifrices and oral rinses. Sodium fluoride delivers a highly reactive fluoride ion; therefore, formulating it with a compatible abrasive is critically important for achieving the anticaries benefit. When fluoride is present in oral fluids (i.e., saliva), fluorapatite, rather than hydroxyapatite, forms during the remineralization process. Fluoride ions (F–) replace hydroxyl groups (OH–) in the formation of the apatite crystal lattice, resulting in a stronger, fluoridated tooth mineral (fluorapatite). Fluorapatite is less soluble than hydroxyapatite, even under acidic conditions. Because fluorapatite is less soluble than hydroxyapatite, it is also more resistant to subsequent demineralization when acid-challenged. Get in touch with the solution by just clicking the following links- Facebook Group- / solutionpharamcy Mobile App - https://play.google.com/store/apps/de... New Channel (Pharmacy Dictionary) / @pharmacydictionary E-Mail for official and other work - solutionpharmacy@gmail.com #solutionpharmacy #Pharmacologyclass #Pharmacognosyvideos #GPAT