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Barbara Sahakian - CNS2023

About CNS2023 The 33rd annual Cambridge Neuroscience Seminar took place on Tuesday September 26th 2023 at Robinson College at the University of Cambridge. We used our annual meeting to highlight the strength in the interdisciplinary approach to tackling dementia and how collaboration, with the communal aim of understanding these diseases and identifying new treatments, is key. Achieving better brain health and wellbeing in older age and early detection of memory problems Abstract: To realise our potential throughout our life and to ensure a flourishing society, it is important to focus on good brain health and wellbeing. Environmental factors and our behaviour can improve our brains, cognition and mental health or detract from it. Our diet, our sleep and our social support systems are all key to improving brain health and cognition and reducing the risk of dementia. Early detection of memory problems in older aged adults, including amnestic mild cognitive impairment (MCI) is also important to utilize current symptomatic treatments and future treatments which are aimed at slowing or halting the underlying disease process. CANTAB Paired Associate Learning has been shown to be sensitive to the early detection of MCI and mild Alzheimer’s disease, in addition poor PAL performance is associated with increased levels of tau and beta-amyloid and reduced hippocampal volume. Cognitive training using games on iPads or mobile phones may be beneficial for improving learning and memory in patients with MCI or stroke. Biography: Professor Barbara J Sahakian DSc FBA FMedSci is based at the University of Cambridge Department of Psychiatry and Behavioural and Clinical Neuroscience Institute. She specializes in various fields including psychopharmacology, neuropsychology, neuropsychiatry, neuroimaging, and neuroethics. She holds numerous prestigious positions, including Honorary Clinical Psychologist at Addenbrooke’s Hospital, Fellow of Clare Hall, Cambridge, and Fellow of the British Academy and the Academy of Medical Sciences. Her work spans cognition and motivation in brain injury, cognitive deficits in depression, and early treatment of Alzheimer’s disease. She has authored over 560 publications in prominent scientific journals and is known for her contributions to neuroscience and mental health policy. Additionally, she has been involved in important initiatives such as the UK Government Foresight Project on Mental Capital and Wellbeing and the World Economic Forum’s Future of Neurotechnologies and Brain Science. Sahakian co-invented the neuropsychological CANTAB and EMOTICOM tests (www.cambridgecognition.com) and the University of Cambridge/PEAK Advanced Training Programme and the Wizard Apprentice Memory Game (www.peak. net). Her recent work also includes research on the effects of COVID-19 on the brain, cognition, mental health, and wellbeing.

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