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Dr Klein is a consultant anaesthetist at Royal Papworth Hospital in Cambridge and also runs the Cambridge Iron Clinic. He identified people with fatigue, suffering from iron deficiency - anemia, who were not getting the treatment they needed. There are many causes for iron deficiency, and in some cases, patients need regular iron infusions, so he set up the Cambridge Iron Clinic to answer this need. Iron deficiency is easily identified by the fatigue, and is also characterised by microblasty or small red blood cells. Dr Klein found that some patients coming to his clinic were actually suffering from B12 deficiency, which also causes fatigue (hence the ancient name "pernicious anaemia"). Vitamin B12 deficiency can also cause absorption problems which result in iron deficiency (with all the symptoms of iron deficiency on top). B12 deficiency can cause megaloblastic anaemia orover-sized red blood cells (megaloblasty). So Dr Klein started offering B12 infusions as well. Dr Klein introduced us to CluB-12, a group of practicing doctors and researchers who have been instrumental in bringing about the new NICE guidelines for Vitamin B12 deficiency. If you haven't already made your doctor aware of the new NICE guidelines, you should do so as the guidelines make it much easier for doctors to make a diagnosis and much more flexible in treatment. https://www.nice.org.uk/guidance/ng239. B12d (this charity) made a number of evidence-based suggestions for the guidelines and we're pleased at the direction that NICE guidelines are going in, even if it is not everything that we could possibly want. Dr Klein will speak about his observations, his research, and his clinic. He will explain what he does far better than I have. He will leave time for questions. Do check out his profile on the web - your searches might find different aspects of his work. Links: https://b12d.org https://www.club-12.org/ https://www.bmj.com/content/383/bmj-2... How to draw up a dose of B12 for injection https://vimeo.com/957765336/e27c475f9... How to inject B12 subcutaneously https://vimeo.com/957767083/2d4e7a3b7...