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Pharmacoeconomics and Patient preferences in chronic inflammatory diseases.

Presenters: Prof. Paweł Kawalec MD, PhD, Jagiellonian University Medical College (JU MC), Poland Prof. Isabelle Huys, KU Leuven, Belgium As the therapeutic landscape for inflammatory bowel disease (IBD) continues to expand, there arises a need to understand how patients perceive and value the attributes associated with both current and emerging treatments. This European patient preference study aimed to quantify IBD patients preferences for treatment and disease-related attributes. A survey incorporating a discrete choice experiment (DCE) comprising 14 attributes with a partial profile design was disseminated among IBD patients. The survey design was informed by a prior literature review, qualitative research with patients, and expert discussions. Multinomial logit models were used to estimate DCE attribute weights and assess potential interactions. Over 1200 IBD patients across 37 countries completed the survey. Detailed results will be presented in the session. Gastrointestinal problems were considered very important to IBD patients next to other quality of life-related attributes affecting IBD patients’ physical, mental, and psychological health such as fatigue, sleeping problems, and risk of surgery. Noteworthy, characteristics that distinguish the different treatments from each other (such as mode of administration and onset of action) seem less important to patients. Observed differences in patients preferences as revealed in the DCE emphasize the imperative role of considering patients preferences in treatment selection.