Cognitive Dysfunction in the Senior Dog & Cat: PART ONE — Pathophysiology and Diagnosis скачать в хорошем качестве

Cognitive Dysfunction in the Senior Dog & Cat: PART ONE — Pathophysiology and Diagnosis

In this video, we explore what happens to the ageing brain in dogs and cats and how veterinarians diagnose Cognitive Dysfunction Syndrome (CDS) — the animal equivalent of dementia. We begin by breaking down the three groups of ageing pets: successful agers, those with mild impairment, and those with severe cognitive dysfunction. The presentation explains the free radical theory of ageing, where inefficient mitochondria and oxidative stress cause a vicious cycle of neuronal damage. Over time, this leads to β-amyloid accumulation, tauopathy, energy deficits, and ultimately nerve cell dysfunction and death The video also highlights the neuropathological similarities between CDS and human dementia, including amyloid plaques, neurofibrillary tangles, microglial activation, and white matter changes. MRI examples demonstrate cortical atrophy, ventriculomegaly, and leukoaraiosis in affected patients We then move into diagnostic strategies, emphasising the importance of distinguishing cognitive decline from other medical or neurological conditions. Tools include neurological exams, metabolic screening, blood pressure checks, and behavioural assessment. A central diagnostic tool is the CADES (Canine Dementia Scale), which scores behaviour across four domains: spatial orientation, social interaction, house soiling, and sleep–wake cycles (pages Finally, the video features a 12-year-old Samoyed whose behavioural changes initially mimicked pain but were ultimately diagnosed as severe cognitive dysfunction with multiple comorbidities Useful link 1) BSAVA Petsavers Ageing Canine Toolkit https://www.bsava.com/petsavers/our-i... 2) article and CADES type questionnaire in cats chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://actualidadveterinaria.wordpre... 3) CADES questionnaire in dogs - https://neurovet.co.uk/downloadable-p... #cognitivedysfunction #PetDementia #SeniorPets #DogDementia #CatDementia #VeterinaryMedicine #VetNeurology #AgeingPets #PetBrainHealth #CanineCognitiveDysfunction #FelineCognitiveDysfunction #VetEducation #AnimalHealth #Neurodegeneration #VeterinaryScience #PetCareTips #SeniorDogCare #SeniorCatCare #CADES #DiagnosingDementia #Alzheimer #Dogzheimers #MRI #β-amyloid #leukoaraiosis 00:00 Introduction 01:15 Pathogenesis 08:51 Diagnosis 09:47 BSAVA PetSavers Ageing Canine Toolkit 14:07 Questionnaires for CDS diagnosis 26:28 12 year old Samoyed - his story 33:24 MRI changes in CDS 39:36 Key Messages