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Cognitive Dysfunction in the Senior Dog & Cat: PART TWO- Management In Part Two, we focus on evidence-based strategies for managing Cognitive Dysfunction Syndrome (CDS) and improving quality of life for ageing pets and their caregivers. The presentation covers dietary manipulation, highlighting the benefits of antioxidant-rich diets, L-carnitine, omega-3 fatty acids (EPA/DHA), vitamins E and C, and medium-chain triglycerides (MCTs) as alternative neuronal energy sources. cognitive dysfunction dementia Pharmacological options include: • Propentofylline, improving cerebral blood flow and supporting glial cell function. • Selegiline (L-deprenyl), a monoamine oxidase inhibitor shown to enhance dopamine/noradrenaline availability and offer neuroprotective effects. • Melatonin and anxiolytics for sleep disturbances and "sundowning". • The video also evaluates experimental treatments, such as cholinesterase inhibitors (e.g., donepezil, phenserine) and adrafinil, explaining their limited evidence base and safety considerations. Since many senior animals have concurrent diseases, the video outlines how to manage comorbidities like hypertension, hyperthyroidism, chronic kidney disease, osteoarthritis, urinary tract infections, and polyneuropathy. Behavioural and environmental enrichment forms a major part of therapy. Strategies include: • Increasing predictability and routine • Sensory stimulation (olfactory, auditory, tactile cues) • Improving home accessibility • Mental and physical enrichment (activity feeding, play) • Feeding adjustments for older pets. Useful links - article and CADES type questionnaire in cats chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://actualidadveterinaria.wordpre... CADES questionnaire in dogs - https://neurovet.co.uk/downloadable-p... The video concludes with key take-home messages on combining dietary therapy, behaviour strategies, pharmacological support, and comorbidity management to optimise patient wellbeing. #CognitiveDysfunction #SeniorPetCare #DogDementiaHelp #CatDementiaHelp #PetDementiaSupport #VeterinaryMedicine #CDSManagement #PetNutrition #BrainHealth #SeniorDogTips #SeniorCatTips #VetNeurology #Selegiline #Propentofylline #Omega3ForPets #EnvironmentalEnrichment #PetBehaviour #VeterinaryCare #HealthyAgeingPets #PetWellbeing #Alzheimer #Dogzheimers 00:00 Introduction 00:52 Dietary manipulation in CDS 08:00 Pharmacotherapy of CDS 12:42 Sundown Syndrome - sleep disorder in CDS 17:06 Experimental work Cholinesterase inhibitors and more 20:16 Managing Comorbidities 25:51 CDS dealing with the behavioural aspects 27:54 Outcome 12yo Samoyed and thank you to his caregiver