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ChargePoint PharmaSafe® Split Butterfly Valves (SBV) powder containment system ensures high integrity worker protection when transferring potent products from process to process. The weighing and dispensing of product from the isolator when API (Active Pharmaceutical Ingredients) typically are handled in pure form, can pose significant risk to operators. ChargePoint PharmaSafe® system can be adapted with several accessories to meet many different process scales and set ups, in any case nanogram level containment performance can be achieved to reduce these associated risks of exposure. This animation shows how a typical isolator dispensing operation may take place with the utilisation of either flexible packaging such as the ChargeBag® or a rigid container. Devices can be integrated to allow the easy, repeatable docking of the product container and SBV Passive connection. A funnel accessory improves the control and accuracy of dispensing through the open valve from within the isolator. Furthermore once the product container has been removed and taken to the next process, the Active connection can be Washed In Place in conjunction with the isolator with the use of dedicated accessories.