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Most people reach for another coffee when their brain is tired—but what if the real issue is how your brain makes and spends energy? In this episode of Peptides and Longevity, Dr. Gregory Kelly joins us to break down what nootropics are, how caffeine impacts focus and mood, and why mitochondrial health and chronobiology matter for sustainable brain performance. Follow Us On Social Media: IG: / holtorfmedicalgroup FB: / holtorfmed ---- Connect with Dr. Gregory: Website: https://www.qualialife.com/people/gre... LinkedIn: linkedin.com/in/gregory-kelly Three Takeaways ✅ Discover what makes a nootropic truly ‘smart.’ Learn how they evolved from early research, why they enhance learning and brain plasticity rather than just provide stimulation, and how to avoid trading short-term focus for long-term side effects. ✅ Master the Goldilocks principle of brain performance. See why caffeine works best in a narrow ‘just right’ range, how over-arousal undermines attention, and how stacking ingredients like theanine and brain-fuel nutrients boosts alertness without the crash. ✅ Rethink brain energy and nutrition. Explore how mitochondrial function, chronobiology, and daily nutrient shortfalls affect memory, mood, and flexibility. About the Guest Dr. Gregory Kelly is a naturopathic physician and the director of product development at Neurohacker Collective, where he guides the development of nootropic, mitochondrial, immune, and healthy-aging formulas. He is the author of ‘Shape Shift,’ was editor of the Journal of Alternative Medicine Review, and a contributor to the Textbook of Natural Medicine, with more than 30 publications indexed in PubMed. Before entering naturopathic medicine, he served as a Navy officer and earned an engineering degree, later redirecting his curiosity toward how people and traditional cultures care for their health. He has taught advanced clinical nutrition, counseling skills, and doctor–patient relationships at the University of Bridgeport and the College of Naturopathic Medicine. With over two decades immersed in supplements, natural medicine, and chronobiology, his work centers on nootropics, anti-aging, regenerative medicine, weight management, sleep, and the timing of biological processes that shape performance and health. #Peptides #longevity #holtorfmedicalgroup