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Pathophysiology of cardiac arrhythmias Cardiac action potential Playlist: • Action potential of cardiac muscle | cardi... Buy Physiology Notes here: Download 📲 Android app for Physiology notes here: https://play.google.com/store/apps/de... 🍏 IOS app: https://apps.apple.com/in/app/myinsti... (use org code:ezlep) 🧑🏼💻 Login in laptop: https://web.classplusapp.com (use org code: ezlep) Visit the website: http://www.physiologyopen.com/ Buy our Practical Physiology 2nd edition book here: 👉 Amazon: https://amzn.in/d/9pKLWns 👉 Flipkart: https://www.flipkart.com/practical-ph... Want to excel in academics: Buy our book The Roadmap for Academic Success: Essential Student Strategies for Time Management, Focus, Beating Procrastination, Learning, and Memory 👉 : https://amzn.in/d/dWDdSG4 Pathophysiology of cardiac Arrhhythmias: The arrhythmias may be either bradyaarhythmias or tachyarrhythmias. There are 3 basic mechanisms by which tachyarrhythmias may occur 1. Enhanced automaticity 2. Triggered automaticity 3. Reentry 1. Enhanced automaticity This type of arrhythmias may poccur due to abnormality in the pacemaker cells. Enhanced automaticity may occurif thereis increase in slope of the pacemaker potential or the Resting membrane potential becomes less negative. This may happen in case of excessive sympathetic stimulation and mild kyperkalemia 2. Triggered automaticity This occurs in cells which are not having automaticity but automaticy is being triggered by someting. It involves due to generation of after-depolarization: After depolarizations are of two types: Early after depolarization which occurs during the repolarization phase of cardiac action potential. It occurs whenever action potential gets prolonged. QT interbal prolonation is a sign of prolonationof action potential duration and thus it may lead to early after depolarization and hence predisposes a person to arrhythmias. Delayed after depolarization occur after the repolarization ends i.e in phase 4 of cardiac action potentia. These after depolarization can lead to generation of impulse before the normal impulse reaches the contractile cells. 3. Reentry circuits: Third mechanism for arrhythmias is reentry or movement of an impulse in a circus movement. If an impulse has 2 paths through which it can pass and these conducting paths differe electrically such that one is fast conducting path and th eother is slow conducting path, in that case of renetry of impulse may occur. Reeentry may occur due to an anatomical defect (anatomical reenetry) or may be due to functional difference in the electrical propery of the cells (functional reentry). Wolff-Parkinson syndrome is a type where arrhthmias occur due to anatomical reentry Watch our other popular playlists: Sensory physiology playlist: • Sensory system Special senses Physiology: • Special senses Physiology CNS physiology: • Central nervous system | CNS Physiology mb... Cardiovascular physiology: • Cardiovascular physiology mbbs 1st year le... Respiratory physiology: • Respiratory system physiology mbbs 1st yea... General Physiology: • General physiology mbbs 1st year lectures Blood physiology: • Blood physiology, pathology, pharmacology ... Renal Physiology: • Renal system physiology lectures | 1st yea... Endocrine physiology: • Endocrine system | Physiology lectures MBB... #cardiovascularphysiology #physiologyopen #mbbs1styear #physiology #physiologylectures #physiologytheory #physiologyopen #cardiovascularsystem