|Tiffeneau-Demjanov rearrangement mechanism|Rearrangement to electron deficient carbon. скачать в хорошем качестве

|Tiffeneau-Demjanov rearrangement mechanism|Rearrangement to electron deficient carbon.

The Tiffeneau–Demjanov rearrangement (TDR) is the chemical reaction of a 1-aminomethyl-cycloalkanol with nitrous acid to form an enlarged cycloketone The Tiffeneau–Demjanov ring expansion, Tiffeneau–Demjanov rearrangement, or TDR, provides an easy way to increase amino-substituted cycloalkanes and cycloalkanols in size by one carbon. Ring sizes from cyclopropane through cyclooctane are able to undergo Tiffeneau–Demjanov ring expansion with some degree of success. Yields decrease as initial ring size increases, and the ideal use of TDR is for synthesis of five, six, and seven membered rings. A principal synthetic application of Tiffeneau–Demjanov ring expansion is to bicyclic or polycyclic systems. Several reviews on this reaction have been published. •Molecular rearrangements|| Rearrangement chemistry :    • Molecular rearrangements|| Rearrangement c...   •Esterification of carboxylic acid and hydrolysis of ester.(BSC chemistry 4th sem):    • Esterification of carboxylic acid and hydr...