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Michael spent most of his life trying to lose weight. He started dieting as a kid, followed every program you can imagine, and watched the weight come off only to return again and again. By his late 50s, his health was unraveling. Blood pressure was climbing, cholesterol was out of control, his heart was failing, and he was staring at a future he did not think he would live long enough to enjoy. Then he decided to try GLP-1 medication. In this episode of The Downsized Dish, Christopher Durham sits down with Michael, a 58-year-old grandfather from the San Francisco Bay Area, who lost an incredible 222 pounds in just 15 months. He went from more than 400 pounds to the 180s, eliminated fast food, silenced the food noise, and followed a medically supervised plan that included GLP-1 therapy, real food, and regular monitoring. Today, Michael is off his blood pressure medication, off cholesterol drugs, and his cardiologist was so shocked by his lab results that he ordered the tests to be run again. His pacemaker has not activated in nearly three years. He donated 20 bags of clothes, went from a size 44 waist to a size 32, and now fits into clothes he never imagined wearing again. In this conversation, Michael shares what it was really like to pay out of pocket for GLP-1s, how he lost weight so quickly, why he refuses to lower his dose during maintenance, what he eats now, and why the fear of regain still sits in the back of his mind. He also talks about therapy, family support, and why he wishes he had started sooner. This is not a story about willpower. It is about access, science, medical care, and what can happen when the right treatment finally meets the right person at the right time. If you are thinking about starting GLP-1s, are struggling with maintenance, or feel like you have tried everything, Michael’s story may be the one you have been waiting to hear. +++++++++++++++++++++++++++++++++++++++ Get your Hume BodyPod today and use our exclusive Downsized code for up to 50% total savings! 👉 Use our Code: THEDOWNSIZED Link to purchase: https://humehealth.com//discount/THED... Start your weight loss journey today! We use Mochi Health: https://app.joinmochi.com/eligibility... Use Laraine’s code for $40 off: QIYGO8. Me Again Iphone GLP-1 App: https://apps.apple.com/us/app/meagain... AMAZON GLP-1 Companion Product Store: https://www.amazon.com/shop/downsized As an Amazon Associate, I earn from qualifying purchases. DOWNSIZED LINKS Website: https://thedownsized.org Be our guest on The Downsized Dish: apply at https://thedownsized.org/downsized-dish/ Https://Thedownsized.Org/ Book The Downsized At Sea Cruise 2026: Https://Thedownsized.Org/Downsized-At... FOR SPONSORSHIPS, BRAND DEALS & COLLABS: https://thedownsized.org/contact/ +++++++++++++++++++++++++++++++++++++++ 00:00 Introduction to the Downsized Dish 01:15 Meet Michael: Background and Family 02:00 Michael's Weight Loss Journey Begins 03:33 Discovering GLP-1s and Initial Challenges 05:30 Remarkable Progress and Lifestyle Changes 06:25 Visual Transformation: Before and After 10:11 Medical Monitoring and Rapid Weight Loss 14:41 Titration and Side Effects 16:32 Maintaining Weight and Final Thoughts 18:44 Unexpected Health Improvements 19:09 Doctor's Reactions and Retesting 21:06 Family Support and Lifestyle Changes 23:43 Diet and Eating Habits 25:16 Clothing Transformation 27:21 Advice for Others Considering GLP-1s 29:39 Therapy and Mental Health 30:51 Fears and Future Outlook 36:45 Concluding Thoughts and Gratitude