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Why does Long COVID persist months—or even years—after the initial infection? In this lecture, we explore two central mechanisms that are increasingly supported by imaging, immunology, and clinical data: 1) Persistently activated T cells 2) Ongoing viral persistence (or viral remnants) Using data from a recent PET imaging study, we walk through how long-COVID patients show evidence of sustained immune activation, even long after acute infection has resolved. Rather than a “recovery gone wrong,” long COVID appears to represent a chronic, dysregulated immune state. If you’re trying to understand long COVID beyond symptom lists and headlines, this lecture focuses on the underlying biology driving persistent disease. 💙 Want to support this work? ☕ Buy me a coffee: https://www.buymeacoffee.com/DrMobeen... 🎥 Become a patron: https://www.patreon.com/mobeensyed?fa... 💵 PayPal: https://paypal.me/mobeensyed?locale.x... 📬 My Substack: https://mobeensyedmd.substack.com/ 🛑 Medical Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health-related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. Courses | DrBeen https://members.drbeen.com/courses Tissue-based T cell activation and viral RNA persist for up to 2 years after SARS-CoV-2 infection | Science Translational Medicine https://www.science.org/doi/10.1126/s... SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC) | Nature Immunology https://www.nature.com/articles/s4159... Postacute COVID-19 is Characterized by Gut Viral Antigen Persistence in Inflammatory Bowel Diseases - PMC https://pmc.ncbi.nlm.nih.gov/articles... Long COVID and SARS-CoV-2 persistence: new answers, more questions - The Lancet Infectious Diseases https://www.thelancet.com/journals/la... What Is the AIP (Autoimmune Protocol) Diet? https://health.clevelandclinic.org/ai...