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In this debut episode of _Galaxy Balance_, host Cory Smith sits down with legendary geneticist and futurist George Church for a wide-ranging conversation on the edge of science and imagination. Together they explore the accelerating frontier of *AI-driven biology*, including protein design, scientific “superintelligence,” and the rise of automated science factories. George discusses the real state of *de-extinction*, from woolly mammoths to dire wolves, and the technologies Colossal Biosciences is building to save endangered species. The conversation also dives into the future of *human reproduction*, IVF breakthroughs, synthetic gametes, and the ethical landscape around editing human embryos. From mirror-life and biosafety to *von Neumann probes, astrobiology, and the search for extraterrestrial life*, this episode spans genomics, planetary science, and the future of intelligent civilizations. George also shares thoughts on AI risks, surveillance for biosecurity, his inspiration from science fiction, and what young scientists should focus on now. A deep, fast-moving, idea-packed episode with one of the most visionary minds in science.