Early Afterdepolarizations EXPLAINED: Triggered Action Potentials & Ionic Mechanisms скачать в хорошем качестве

Early Afterdepolarizations EXPLAINED: Triggered Action Potentials & Ionic Mechanisms

💡 Early Afterdepolarizations & Triggered Action Potentials EXPLAINED Discover how early afterdepolarizations (EADs) lead to triggered action potentials and their underlying ionic mechanisms in this high-yield video! Perfect for medical students, USMLE prep, and cardiology enthusiasts looking for a clear explanation of cardiac electrophysiology. What You’ll Learn in This Video: ✔️ Definition & Mechanisms: What are early afterdepolarizations (EADs) and how do they occur? How triggered action potentials are generated from EADs. ✔️ Ionic Mechanisms: Role of calcium and potassium currents in EAD formation. How altered ion channel dynamics lead to arrhythmogenic activity. ✔️ Clinical Relevance: Why EAD-triggered activity is critical in conditions like long QT syndrome and other arrhythmias. USMLE high-yield tips and mnemonics to remember these concepts. ⏰ Timestamps for Easy Navigation: 00:00 Definition of afterdepolarization and classification (EAD, DAD) 00:39 Normal ventricular action potential phase 4 01:02 Phase 0 Depolarization 01:40 Phase 1 Initial repolarization 02:03 Phase 2 Plato 03:30 Phase 3 Repolarization 04:40 Sodium Potassium pump 05:23 Sodium Calcium exchanger 06:24 Definition of Early afterdepolarization and Delayed afterdepolarization 06:50 EAD- triggered activity 07:54 Four components of EAD-triggered activity 08:31 Conditioning phase (Repolarization prolongation) 10:10 Repolarization duration and QT interval 11:17 2 ways of L-type calcium inward current inactivation 11:55 Ionic Calcium mechanism in EAD formation 13:50 Soidum Calcium exchanger current role in EAD formation 15:16 Sodium Calcium exchanger current role in late phase 3 16:47 Propagation of Triggered action potential 18:40 Role of GAP junctions in Triggered action potential propagation 19:26 Repolarization reserve and Triggered action potential propagation https://t.me/foxterRier_med 💬 Question for You: Have you ever encountered a case where early afterdepolarizations played a role in arrhythmias? Share your insights or questions in the comments below! 😊 👍 Help Us Grow: Like this video if you found it helpful. Subscribe for more high-yield medical content. Share with classmates, colleagues, or anyone interested in cardiac electrophysiology! ⚠️ Disclaimer: This video is intended for educational purposes only and does not replace professional medical advice. Always consult a qualified healthcare provider for clinical decision-making.