The science behind weight loss drugs: what they are and how they work скачать в хорошем качестве

The science behind weight loss drugs: what they are and how they work

The new weight loss drugs are mainly recognised by their brand names of saxenda, ozempic, wegovy, mounjaro and zepbound. These are medicines that contain the active drugs liraglutide , semaglutide or tirzepatide. This video outlines the discovery of these drugs and explains their #pharmacology, giving a detailed explanation of what they are, how they act in the body to reduce blood sugar levels and bring about weight loss and why they need to be injected to be effective. 0:00 What are the weight loss drugs: brand names, active ingredients, drug action 1:22 Glucagon-like peptide 1 (GLP-1) 2:50 Gastric inhibitory peptide (GIP) 3:42 Metabolic effects of GLP-1 and GIP 5:25 The pancreas: structure and cell types 7:28 Insulin and glucagon regulate blood glucose levels 9:00 GLP-1 and GIP are agonists at Gs-protein coupled receptors 12:00 Why does GLP-1 inhibit glucagon release? 13:10 Development of GLP-1 agonists (mimetics) 15:44 Development of GIP/GLP-1 co-agonist (mimetic) #Wegovypill #Wegovy_mechanism #GLP1agonist