How can we use RNA sequencing to figure out how a drug works? скачать в хорошем качестве

How can we use RNA sequencing to figure out how a drug works?

RNAseq is such a powerful tool! In this video I discuss how using the awesome power of RNA sequencing we can narrow down the potential mechanism of a novel drug. The key to this method is homeostasis!  Learning objectives  Explain the challenges associated with elucidating the mechanisms of action of drugs, considering the intricate nature of drug-target interactions and the limitations of current methods. Explain and examine utilizing RNAseq techniques to identify potential mechanisms of action for drugs, utilizing transcriptomic data to uncover gene expression changes and pathways involved. Evaluate the significance of homeostasis in utilizing RNAseq to investigate a drug's mechanism of action. Exploring how biological systems attempt to maintain equilibrium in the presence of a drug - which by definition perturbs biological processes. Recognize the dual role of homeostasis in regulating inhibited proteins, understanding how it can both upregulate and downregulate the expression and activity of targeted proteins in response to drug treatment.