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Infections after Transplant

Summary: Several types of infection can occur after a stem cell or bone marrow transplant and can complicate recovery for patients. This presentation describes the infection risks during the posttransplant period, therapies to treat them, and some measures to prevent them. Presenter: Jennifer Cuellar-Rodriguez MD, National Institutes of Health Transplant and Cellular Therapy Clinical Program To read the transcript, go to: https://www.bmtinfonet.org/video/infe... Highlights: Infection risks from stem cell transplantation can be divided into three periods: pre-engraftment, early engraftment, and later engraftment. Patients are at highest risk for infection in the pre-engraftment period when their immune system is severely compromised. In the early engraftment period, as the immune system begins to recover, preventing graft-versus-host-disease and opportunistic infections becomes a major concern. Posttransplant infections may be prevented by three main strategies: preventive medicines, vaccines, and lifestyle modifications. April 2023, Part of the Virtual Celebrating a Second Chance at Life Survivorship Symposium The presentation is 32 minutes long followed by 26 minutes of Q & A Key Points: (01:47): A pre-transplant evaluation assesses an individual’s risk of getting infections after transplant. (05:42): Infections are common early after transplant but become less common over time. (11:28): After transplant, when patients can return to their home community, they have greater exposure to respiratory viruses, gastrointestinal viruses, and infections associated with food and water. (12:47): Transplant recipients who relapse or who have graft-versus-host disease (GVHD), have an increased risk of infection. (13:17): Posttransplant infections may be prevented by medications such as antibiotics, antifungals, and antivirals; vaccines, and lifestyle modifications. (18:16): Following food safety recommendations is crucial for transplant recipients with a weak immune system. (22:42): Pets can have many emotional benefits for transplant recipients, but they can also carry a significant number of bacteria or parasites that can be harmful. (25:26): Outdoor activities have many health benefits for transplant recipients. However, precautions should be taken when doing outdoor activities including gardening and yard work. (26:18): When planning to travel after transplant, consult your transplant team about whether it is safe, and precautions you should take to reduce your risk of infection. (29:41): Respiratory viral infections are common after patients return to the community. Frequent handwashing, minimizing contacts, and wearing a mask are important preventive measures. Meet the speaker: https://www.niaid.nih.gov/research/je... WHO WE ARE: BMT InfoNet is dedicated to providing patients and their loved ones with emotional support and high quality, easy-to-understand information about blood stem cell transplants (bone marrow, peripheral blood and cord blood) and other cellular therapies. Whether you are just beginning your transplant or cellular therapy journey, or learning to manage the joys and challenges of survivorship, BMT InfoNet is here to help before, during and after treatment. Our goal is to empower you with credible information and emotional support, so that you can take a more active role in decisions affecting your health. http://www.bmtinfonet.org VISIT US ON SOCIAL MEDIA:   / bmtinfonet     / bonemarrowstemcelltransplantclub     / bmtinfonet     / bmtinfonet     / bmt-infonet