Obesity Genetics Specialist Giles Yeo Says Your Brain HATES IT When You Lose Weight скачать в хорошем качестве

Obesity Genetics Specialist Giles Yeo Says Your Brain HATES IT When You Lose Weight

Obesity genetics specialist, Giles Yeo talked about this on a podcast. In this clip (posted to TikTok) he explained that your brain makes weight loss harder over time. This includes compensatory changes to your appetite and energy expenditure, and these are largely outside of your conscious control. I have been talking about obesity and obesity genetics for years and every time I do, I get at least a little backlash of people saying things like "stop making excuses for fat people!". This isn't "making excuses", it is discussing biological phenomenons. Understanding these is important because it allows people to be fully informed, and also to find ways to get past these hurdles more effectively. For example, if your energy expenditure (referred to as 'metabolism') decreases when you lose weight, can you counter this by keeping your activity level high? If your appetite increases as you lose weight, can you counter this with dietary changes? Or in severe cases, would medication be necessary? The point is, if the smartest obesity researchers in the world all discuss reasons that long-term weight loss is difficult for people, making it sound like it is very easy for everyone to lose weight and keep it off can paint a misleading picture for long-term weight management. References: Recent advances in understanding body weight homeostasis in humans. Thrifty genes for obesity, an attractive but flawed idea, and an alternative perspective: the ‘drifty gene’ hypothesis The genetics of obesity: from discovery to biology How Strongly Does Appetite Counter Weight Loss? Quantification of the Feedback Control of Human Energy Intake Physiology of the weight-loss plateau in response to diet restriction, GLP-1 receptor agonism, and bariatric surgery Quantification of the effect of energy imbalance on bodyweight