Electrophilic Addition to Conjugated Dienes: Kinetic vs. Thermodynamic Control скачать в хорошем качестве

Electrophilic Addition to Conjugated Dienes: Kinetic vs. Thermodynamic Control

Learn how to predict the products of electrophilic addition reactions to conjugated dienes, such as the reaction with a hydrogen halide, and understand the effect of temperature on the reaction outcome. This lecture video discusses how the reaction proceeds through a resonance-stabilized allylic carbocation intermediate, leading to both 1,2- and 1,4-adducts. Explore the difference between kinetic control (favored at low temperatures) and thermodynamic control (favored at high temperatures). Timestamps 00:00 Introduction and Learning Goals 00:34 Review: Electrophilic addition to an alkene (hydrohalogenation) 01:22 Electrophilic addition to a conjugated diene 01:41 Mechanism 02:48 Defining the 1,2- and 1,4-adducts 03:48 Energetics of the reaction: Hydrochlorination of butadiene example 04:16 Kinetic vs Thermodynamic Control for 1,2- and 1,4-addition 08:28 Example: Hydrobromination of butadiene 09:19 Example: Electrophilic addition to a substituted diene 10:33 Electrophilic Addition of Br2 to Conjugated Dienes