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Speaker: Dr Mark Miller, Principal Investigator, Biology, San Diego Supercomputer Center Abstract: The CIPRES Science Gateway is a public resource that enables browser and RESTful access to phylogenetics codes run on high performance compute resources available through the XSEDE program. Over the past five years, CIPRES has run half a million jobs for 12,000 scientists around the world, and enabled more than 1,700 peer reviewed publications. This talk will provide an overview of the evolution of the CIPRES Science Gateway: the challenges faced and lessons learned in launching new services in a production resource with a large user base. The talk will also describe plans for implementing the CIPRES Notebook Environment, which will provide access to HPC resources via an interface based on the Jupyter notebook project. The Jupyter notebook represents an exciting new paradigm for interactive scientific computing, and incorporating it into CIPRES will enable many capabilities that are not readily available to many phylogenetics researchers.