Rewriting Cancer's Script: Insights from Saturation Genome Editing скачать в хорошем качестве

Rewriting Cancer's Script: Insights from Saturation Genome Editing

The rapid evolution of liquid biopsy technologies and epigenetic profiling is accelerating progress toward earlier and more accurate cancer detection. Among these innovations, cfDNA methylation analysis has emerged as one of the most promising approaches for identifying cancer at its earliest stages. To explore this potential, Dr. Smiths S. Lueong (Priv.-Doz. Dr. rer. nat.), Senior Scientist at University Hospital Essen, presented new insights into how methylation patterns in cell-free DNA can be leveraged for multi-cancer early detection. His work focuses on the development of NGS-based strategies capable of profiling complex epigenetic signatures from minimally invasive liquid biopsy samples. In this webinar, Dr. Lueong highlighted recent data demonstrating the biological significance of cfDNA methylation changes during early carcinogenesis and tumor classification. He discussed real-case examples, analytical challenges, and the complexities of interpreting methylation signals in clinical and pre-diagnostic settings. He also examined how integrating epigenetic biomarkers with NGS technologies paves the way toward more precise, scalable, and clinically actionable cancer detection tools that could shape the future of oncology diagnostics.