Paper Discussion 6 | NEET MDS 2019 скачать в хорошем качестве

Paper Discussion 6 | NEET MDS 2019

1. Aggregatibacter actinomycetemcomitans (Aa) is a major risk factor for localized aggressive periodontitis (LAP; Fine et al. 2007) and is used to induce the symptomatic chronic inflammatory condition in animal models (Schreiner et al. 2003; Garlet et al. 2005, 2007; Trombone et al. 2009; Li et al. 2010). Aa is particularly susceptible to the DNA gyrase inhibitor, ciprofloxacin (Hoogkamp-Korstanje & Roelofs-Willemse 2000, Muller et al. 2002). In one study mentioned prior, they compared the effect of seven antibiotics on A. actinomycetemcomitans. Here are the results. A total of 60 isolates of A. actinomycetemcomitans recovered from 43 individuals with gingivitis or periodontitis were tested. In addition, laboratory strains UP-6 and JP2 were analysed. The E-test was employed in order to determine minimal inhibitory concentrations (MIC) of antibiotics ampicillin/sulbactam, roxithromycin, azithromycin, doxycycline, metronidazole, ciprofloxacin, and moxifloxacin. A. actinomycetemcomitans was highly susceptible to both fluoro-quinolones (MIC90 of 0.006 microgram/mL of ciprofloxacin and 0.032 microgram/mL of moxifloxacin). Good susceptibilities were found for ampicillin/sulbactam and doxycycline (MIC90 of 0.75 microgram/mL and 1 microgram/mL, respectively), and moderate susceptibilities for azithromycin (MIC90 of 3 microgram/mL). Most strains were resistant to metronidazole and roxithromycin. Due to reported favourable pharmacokinetics, the fluoro-quinolone moxifloxacin appeared to be a promising candidate for adjunctive systemic antibiotic therapy in periodontal infections with A. actinomycetemcomitans. 2. A lingual or cingulum rest seat should be V shape d when viewed in cross section.This geometry prevents migration of the abutment away from the removable partial denture framework. Hi lovely people, drop a mail @ proudtobedentist@gmail.com for any queries. Also check out our website ptbdacademy.com. Best wishes.