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For centuries, smallpox was a deadly threat with no real protection. It scarred faces, killed children, and returned again and again — until medicine finally took a decisive step forward. In this video, I explain how smallpox was stopped and why this breakthrough became a true medical revolution. Through the story of Lady Mary Wortley Montagu — a woman who survived smallpox herself and lost her brother to the disease — we see how personal experience and courage forced European medicine to rethink the very idea of disease prevention. I take you along the path toward vaccination: from practices observed in the Ottoman Empire, through fear, resistance, and controversy in Europe, to the scientific breakthrough that permanently changed medicine. This is a story about risk and doubt, mistakes and opposition — and about the moment when smallpox was transformed from an unavoidable killer into a disease humanity learned how to stop. #history #vaccination