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This video explains the role of pcsk9 inhibitors and statins in up-regulating the LDL receptor levels thereby decreasign LDL-cholesterol. pcsk9 inhibitors increases the expression of ldl receptors and likewise statins also increases the expression of ldl receptors. Mechanism of pcsk9 inhibitors and stains in increasing ldl receptors is explained in detail. I will uploading videos one to two times per week, for regular updates SUBSCRIBE to this channel by clicking the red button below my videos or in the link below: https://goo.gl/eMs6rw If you find these videos helpful, spread the news and SHARE with your friends. For short write up of theory on USMLE Biochemistry and other topics on food and nutrition, obesity, weight loss tips you may visit my site: http://www.drmungli.com/ You can follow my Facebook page Biochemistry Made Easy: https://goo.gl/23S9Y7 checkout other awesome channels to learn biochemistry and other subjects from: ThePenguineProf: https://goo.gl/ySNURB Osmosis: https://goo.gl/d1zBs1 Armando: https://goo.gl/jcYwwR Khan Academy: https://goo.gl/7YmIf9 Nucleus Medical Media: https://goo.gl/xdlqsr Trending medical youtube channels: https://goo.gl/nUuJOL 20 useful sites for medical students: https://goo.gl/aPnc19 Biochemistry single line questions site: https://goo.gl/PFCewk Pictures and video graphics used in my videos came from https://pixabay.com which are CC0 creative commons, free for use commercially and no attribution needed. Some of the pictures are downloaded from http://pexels.com Free to use commercially with no attribution needed. Some of the pictures are downloaded from Wikimedia commons https://commons.wikimedia.org/wiki/Ma... Appropriate attribution is given to these figures wherever applicable. Sounds used in my videos mostly came from copyright free sound from https://www.bensound.com/