GoEQIPD Webinar Part 2 - Kim Wever: Systematic review & meta-analysis in animal studies скачать в хорошем качестве

GoEQIPD Webinar Part 2 - Kim Wever: Systematic review & meta-analysis in animal studies

The GoEQIPD webinar on March 16, 2023 was presented by Kim Wever from Radboud University Medical Center Nijmegen discussing how systematic reviews and meta-analysis can help in translating animal study results and how they contribute to increasing robustness and scientific rigor. http://go-eqipd.org/ 0:00 Introduction 1:24 No financial conflicts of interest 2:36 Preclinical systematic reviews 7:33 A short history of SRs 9:11 Benefits of preclinical SRs 9:37 Overview of available evidence 13:36 Identify knowledge gaps 16:01 Reporting of quality indicators 17:57 SYRCLE'S ROB tool for animal studies 18:55 Risk of bias assessment 27:07 Informing animal studies Choice of rat strain 29:11 Informing clinical trials 30:36 Background: publication bias 31:14 PB and synthesis of evidence 31:42 Assessing PB: funnel plot asymmetry 33:03 Assessing PB: trim and fill analysis 35:18 Tools per SR phase 37:13 Educational resources 42:25 Meta-analysis: forest plots