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Kriben Govender (Honours Degree in Food Science & Technology) and James Shadrach (Honours Degree in Psychology) interview The Probiotic Advisor- Dr Jason Hawrelak on how to optimise your Gut Microbiome using DNA based Stool Testing, Diet, Prebiotics and Probiotics. Dr Hawrelak is Head of Research at ProbioticAdvisor.com. His passion for gastrointestinal health, the GIT microbiota, and probiotics was ignited during the final year of his undergraduate training. Subsequently, Dr Hawrelak did his Honours (First Class) and PhD degrees in the areas of the gastrointestinal microbiota, IBS, and the clinical applications of pre- and probiotics. He has written extensively in the medical literature on these topics – including 16 textbook chapters – and his research has been cited over 800 times. Topics discussed: 03:20 The digestive disease epidemic and the associated causes 05:28 What is the Gut Microbiome vs Gut Microbiota 07:25 DNA Based Stool Testing 08:05 How to interpret a Stool Testing Report 11:55 Firmicutes, Bacteroidetes and Proteobacteria 12:47 The negative effects of Proteobacteria endoxins/Lipopolysaccharides 15:20 Strategies to reduce Proteobacteria genera 16:54 Hydrogen sulfide gas producers - eg Desulfovibrio, Bilophila 18:02 Methane producing Archae- Methanobrevibacter. smithii 19:12 Using Prebiotics to decrease abundance of Pathobionts - Partially Hydrolysed Guar Gum, fructo-oligosaccharides (FOS) Inulin, Lactulose, Galacto-oligosaccharides (GOS), Acacia Fibre 20:30 What are Short Chains Fatty acids, eg Butyrate, Acetate, Propionate 21:40 Impact of Bile Acid Supplements 23:30 Peace Keeping Bacteria- Lactobacilli, Bifidobacteria, Akkermansia 25:45 Leaky Gut 26:35 Increasing levels of the Peace Keeping to improve gut integrity 29:25 Beneficial Butyrate Producing Bacteria 32:24 Gut healing properties of Butyrate 33:53 Foods that feed good bacteria- polyphenols, resistant starch 34:43 Exogenous Butyrate supplementation 37:00 Gut Dybiosis and Mental Health 37:57 Endotoxin, brain inflammation and the link to depression/ anxiety 39:40 Foods/ Diets to avoid to prevent depression and anxiety 40:50 The importance of fibre for health and mental health 42:10 The impact of sleep on microbiome diversity 43:00 The synergistic impact of poor diet and sleep deprivation 43:50 What is Small Intestinal Overgrowth (SIBO)? 45:22 SIBO and the oral microbiome 46:35 Is there a place for a mouth probiotic? 47:10 The negative impact of proton pump inhibitors 47:30 Lactobacillus reuteri DSM 17938 for gum disease, and SIBO 48:40 Helminthic Therapy, hook worms and celiac disease 50:20 Are parasites a problem? Giardia, Blastocystic hominis, Dientamoeba fragilis 52:55 The role of commensal protozoa and fungi 55:05 Are probiotics effective after a course of antibiotics? (study discussed in a previous podcast - Episode 3 - The Truth about Probiotics) https://podcast.nourishmeorganics.com... 58:25 How to effectively use probiotics? 01:04:45 Bifidobacterium lactis HN019 and gut transit time 01:06:20 Digestive enzymes, Hydrochloric Acid Brought to you by: Nourishmeorganics- Gut Health Super Store- Shine from the Inside https://www.nourishmeorganics.com.au/ Shop Probiotics (10% off using code: jason) https://www.nourishmeorganics.com.au/... Shop Prebiotics (10% off using code: jason) https://www.nourishmeorganics.com.au/... Shop Digestive Enzymes (10% off using code: jason) https://www.nourishmeorganics.com.au/... Show Links: Connect with Jason Hawrelak: https://www.probioticadvisor.com/ Connect with Kriben Govender: Facebook- / guthealthgurus Instagram- / guthealthgurus Youtube-https://www.youtube.com/c/guthealthgu... Telegram: https://t.me/guthealthgurus Gut Health Gurus Facebook Group: / nourishmeorganics Deuterium Depletion Support Group : / mitowellness jason hawrelak, microbiome, dr. jason hawrelak, jason hawrelak podcast, functional medicine kriben govender, kriben govender podcast, leaky gut, probiotics, gut brain axis