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In this video, the Foundation for Prader-Willi Research announces our first round of Research Awards in 2020 totaling $912,251. FPWR is dedicated to supporting research that advances the understanding and treatment of Prader-Willi syndrome (PWS) and to that end, has awarded over $14,000,000 to research since 2003. In this webinar, Dr. Theresa Strong reviews each of the 9 funded grants, sharing why we're excited about them and what their potential long-term contribution could be. The 9 grants reviewed in this webinar include: Long non-coding RNAs transcribed from Prader-Willi syndrome locus: key regulators of gene expression. Pawel Grzechnik, Univ Birmingham UK. Novel Transcriptomic Signatures in Blood and Brain Predictive of Behavioral Issues in PWS. David Godler, Murdoch Children’s Research Institute. The role of the placenta in PWS: mapping the expression of PWS genes. Anthony Isles, Cardiff University Assessment of epigenetic driven circadian rhythm defects in neurons from individuals with PWS (Year 2). Larry Reiter, Univ Tennessee HSC Identification of critical periods for the neurodevelopmental and behavioral effects of oxytocin (YEAR 2). Sebastien Bouret and Francoise Muscatelli, INSERM The functional development of hunger neurons in Prader-Willi Syndrome (year 2). Marcelo Dietrich, Yale University ' Gene Therapy of Obesity in Prader-Willi Syndrome by an Autoregulatory BDNF Vector. Lei Cao, The Ohio State University. Precise epigenome editing as a novel therapeutic opportunity for Prader-Willi syndrome. Claudio Mussolino, University of Freiburg Engineering epigenome editing tools for sustained reactivation of maternal PWS genes. Nahid Iglesias, Duke University