Biochemistry Chapter 11 | Porphyrias: Heme Synthesis Regulation, AIP and PCT For Step 1 скачать в хорошем качестве

Biochemistry Chapter 11 | Porphyrias: Heme Synthesis Regulation, AIP and PCT For Step 1

Try Med School Bootcamp for Free: https://bootcamp.com/med-school In this Biochemistry Chapter 11 lesson, we walk through porphyrias by mapping the heme synthesis pathway step by step, then tying each enzyme to the classic USMLE Step 1 clues you are expected to recognize. You will also learn the rate limiting step, the lead inhibited enzymes, and how pathway regulation explains common triggers and treatments. Covered in this video: • Heme synthesis and key intermediates • ALA synthase regulation and common triggers • Lead inhibited enzymes • Sideroblastic anemia buzzwords • AIP presentation, triggers, diagnosis, treatment • PCT rash, Woods lamp urine, risk factors • High yield differential • Step style question walk through with carbamazepine ⏱️ Timestamps 00:43 Heme synthesis overview and porphyrias roadmap 01:06 High yield porphyrias: AIP and PCT 03:34 ALA synthase, rate limiting step, B6 04:18 ALA dehydratase and lead inhibition 05:25 Uroporphyrinogen III synthesis and pathway flow 08:26 Ferrochelatase adds iron and lead inhibition 09:26 Sideroblastic anemia preview 10:27 AIP overview: PBG deaminase deficiency 11:27 PCT overview: UROD deficiency and skin findings 12:54 Heme synthesis regulation and sideroblastic anemia 24:24 Acute intermittent porphyria deep dive 36:02 Porphyria cutanea tarda deep dive 44:18 Step style question walk through If it helps you out, give it a like, leave your questions in the comments, and subscribe for more Bootcamp videos. TikTok:   / medschoolbootcamp   INSTAGRAM:   / medschoolbootcamp   #medschoolbootcamp #medicine #Medical #MedStudent #MedicalStudent #MedSchool #MedicalSchool #Doctor #Resident #Hospital #MD #Med #Anatomy #Science #Whitecoat #WhiteCoatCeremony #MS1 #ms2 ______________________________________________________________ porphyrias, heme synthesis, hem synthesis, acute intermittent porphyria, AIP, porphyria cutanea tarda, PCT, ALA synthase, ALA dehydratase, porphobilinogen deaminase, PBG deaminase, uroporphyrinogen decarboxylase, urod, ferrochelatase, lead poisoning ALA dehydratase ferrochelatase, sideroblastic anemia, basophilic stippling, ringed sideroblasts, cytochrome P450 inducers, carbamazepine AIP trigger, barbiturates phenytoin rifampin, hemin treatment, glucose treatment porphyria, port wine urine, urine darkens on standing, woods lamp fluorescence, photosensitivity blistering rash, dorsum of hands rash, hepatitis C PCT, hemochromatosis PCT, Step 1 biochemistry, medical student biochem, USMLE porphyria review, Med School Bootcamp biochemistry