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Your immune system isn’t just about immune cells — it depends on the integrity of your gut lining and the metabolic activity of your microbiome. In Part 2 of this microbiome–immune connection series, Dr. Katrina Coulter, board-certified Infectious Disease physician, explains how gut microbes help regulate inflammation, strengthen the intestinal barrier, and support immune balance through the production of short-chain fatty acids. This video explores why gut barrier health is foundational to immune resilience and how everyday lifestyle choices can either support or disrupt this system. In this video, you’ll learn: Why the gut lining acts as an immune “firewall” How dietary fiber fuels beneficial gut microbes The role of short-chain fatty acids (especially butyrate) in barrier integrity How antioxidants help control immune-related oxidative stress Practical ways to support your gut lining and reduce inflammation Understanding this connection helps explain links between gut health, chronic inflammation, autoimmune conditions, and overall immune resilience. 👉 Subscribe to the channel and turn on notifications so you don’t miss the rest of the series. 0:00 Intro — From immune training to immune regulation 1:18 The gut lining: your immune firewall 2:18 What happens when the gut barrier weakens 3:00 Microbial metabolites explained (SCFAs) 3:40 Butyrate and barrier protection 5:05 Inflammation: helpful vs harmful 5:38 Antioxidants and oxidative stress control 7:22 How microbes enhance antioxidant effects 8:19 Where vitamin D fits 9:32 What disrupts gut barrier health 10:36 Practical ways to support your gut lining 11:58 Closing and how you can find me DISCLAIMER: The content provided in this video is for informational and educational purposes only and is not intended as medical advice. This video does not create a doctor-patient relationship between Dr. Coulter and you. Always seek the guidance of your physician or other qualified health professional with any questions you may have regarding your health or a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have seen or heard in this video. The information contained in this video is not intended to diagnose, treat, cure, or prevent any disease. Use of the information provided in this video is at your own risk. The creator of this video assumes no responsibility or liability for any errors or omissions in the content of this video.