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Dr. Dayan Goodenowe's clinical trial showed 41% of Alzheimer's patients improved cognition with plasmalogen supplementation—a breakthrough in a field where drugs typically aim to slow decline by months. We discuss the science, testing, and practical protocols. If you would like to support our channel please consider joining our Patreon / modernhealthspan ~~~~~~~~~~~~~~ Prodrome (25% off: MODERN) https://tinyurl.com/3z26j9up ProdromeGlia, ProdromeNeuro Renue By Science (10% off: MHS) https://tinyurl.com/bdew4bfs NMN Powder • Lipo NR BiOptimizers (15% off: MHBIO) https://bit.ly/47VAa8f - Magnesium Breakthrough Seeking Health (10% off: Richard10) https://crrnt.app/SEEK/-dm0MyrQ, Histamine Nutrients https://crrnt.app/SEEK/EpM7paAO NMN Bio (15% off: MODERN) https://tidd.ly/46llBuJ Magnesium, https://tidd.ly/45HEIiw NMN Stemregen (15% off: MODERN) US only https://tinyurl.com/45z968yr Wellness Extract (10% off: MODERNWE) http://wellnessextract.com/RICHARDWE Geranylgeraniol • Vit E n1o1 (10% off: Modern) https://tidd.ly/3IczGRW - Nitric Oxide Lozenges AX3 Life (20% off: MODERN20) https://tinyurl.com/2t3w26nw - Astaxanthin Oxford Healthspan (15% off: MHS) https://tinyurl.com/hrxfnzpn - Spermidine Qitone (10% off: HEALTH10) https://tidd.ly/4jGklry Qitone Esters Powder ProHealth* (15% off: MODERN) https://prohealth.pxf.io/aObQRR NMNH 500mg These are affiliate links - using them supports the channel at no extra cost to you. ~~~~~~~~~~~~~~ Plasmalogens are phospholipids comprising 20% of brain content that decline after age 60. Dr. Dayan Goodenowe, the biochemist who developed blood testing for plasmalogens and created the first effective supplementation protocol, joins me to discuss his recent clinical trial results. In 2021, his trial of 22 cognitively impaired participants showed 41% improved cognition and 82% either improved or stabilized—unprecedented in Alzheimer's research. We explore why plasmalogens are critical for myelin, neurotransmitter release, and brain structure; why previous supplements failed for a century; how alkyl-glycerol precursors bypass age-related decline; and the difference between omega-3 (neuronal) and omega-9 (myelin) formulations. Practical takeaways include: testing protocols, optimal dosing strategies, who should consider supplementation, contraindications for ADHD/bipolar, and why this appears most effective as prevention before decline. Dr. Goodenowe also discusses ongoing research in MS, Parkinson's, autism, and his vision for community-based health programs. 📚 Chapters 0:00 Introduction: The Plasmalogen Discovery 1:36 The Clinical Trial: 41% Improved Cognition 7:14 What Are Plasmalogens? Where They're Found in the Body 13:05 Why You Can't Get Plasmalogens from Diet 18:02 The Serendipitous Discovery of Plasmalogen Deficiency 23:38 Can the Brain Actually Regrow? 29:16 Plasmalogens in ALS and Neurological Diseases 33:19 Age-Related Plasmalogen Decline and Muscle Mass 41:46 What Are Plasmalogen Precursors and How Do They Work? 46:50 Plasmalogen Pharmacokinetics: How Long Do They Last? 56:45 Next Steps: Clinical Trials and Community Health 1:04:04 Using MRI and Blood Tests to Track Brain Recovery 🌐Links in this video Dr Goodenowe's home page https://drgoodenowe.com/ Prodrome home page https://prodrome.com/ #Plasmalogens #brainhealth #healthyaging