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As we age, the body processes medications differently. After 60, common prescriptions and over-the-counter drugs — including NSAIDs, aspirin, proton pump inhibitors, sleep medications, and blood pressure drugs — may interact in ways that quietly increase cardiovascular risk. evidence-based discussion, Dr. Annette Bosworth, MD (Dr. Boz) explains how aging affects liver metabolism, kidney clearance, blood pressure regulation, and drug sensitivity. She explores how polypharmacy — the use of multiple medications — can increase the risk of heart attack, stroke, internal bleeding, falls, and cognitive decline. This video is not about fear. It’s about informed decisions. Medication reviews, lifestyle optimization, and evidence-based prevention strategies can significantly reduce unnecessary risk while maintaining the benefits of essential therapies. If you are over 60, caring for aging parents, or managing multiple prescriptions, this discussion could help you ask better questions at your next medical appointment. Always consult your healthcare provider before making changes to any prescribed medication. ⏱️ TIME STAMPS WITH EMOJIS 00:00 ⚠️ The Hidden Risk After 60 01:05 🧬 How Aging Changes Drug Metabolism 02:38 💊 NSAIDs & Blood Pressure Risk 04:13 🩺 Why Over-the-Counter Isn’t Always Safe 06:23 ❤️ Aspirin: Protection or Bleeding Risk? 08:04 🧠 Stroke & Internal Bleeding Concerns 10:22 🧪 PPIs & Nutrient Deficiency 12:46 🦴 Bone Health & Fracture Risk 15:02 😴 Sleep Medications & Fall Risk 16:43 🧠 Cognitive Decline Concerns 18:57 🔄 Polypharmacy Explained 20:35 ❤️ Heart Rhythm & Drug Interactions 22:17 📋 Medication Review Strategy 23:17 🚨 Early Warning Signs to Watch 24:59 ✅ Safe Prevention Strategy medications after 60, stroke risk seniors, aspirin after 60, NSAIDs heart risk, polypharmacy dangers, blood thinners elderly, proton pump inhibitors risks, PPI long term effects, benzodiazepines elderly risk, medication interactions seniors, heart attack prevention over 60, aging and drug metabolism, Harvard Health medications, Mayo Clinic senior health, NIH geriatric research, blood pressure medication risks, kidney function aging, fall risk elderly medications, dementia medication risk, cardiovascular prevention seniors #Over60Health #SeniorHealth #MedicationSafety #StrokePrevention #HeartHealth #Polypharmacy #HealthyAging #AspirinRisk #NSAIDWarning #BloodPressureControl #BrainHealth #FallPrevention #LongevityTips #MedicalResearch #AgingWell #DoctorAdvice #PreventStroke #ElderlyCare #HealthEducation #DrBoz 💥 POWERFUL VIRAL TOP 5 TIPS Schedule a dedicated medication review at least once per year after age 60. Never combine over-the-counter pain relievers with prescriptions without asking your doctor. Track subtle symptoms like dizziness, bruising, fatigue, or confusion. Prioritize lifestyle interventions that reduce dependency on high-risk medications. Never stop medications abruptly — tapering often requires supervision. 📚 REFERENCES National Institutes of Health (NIH) – Aging and Pharmacokinetics Centers for Disease Control and Prevention (CDC) – Cardiovascular Disease Risk U.S. Preventive Services Task Force (USPSTF) – Aspirin Use Guidelines American Heart Association (AHA) – Blood Pressure & Stroke Risk New England Journal of Medicine – ASPREE Trial (2018) American Geriatrics Society – Beers Criteria Harvard Health Publishing – Medication Safety in Older Adults Mayo Clinic – Polypharmacy and Aging FDA Safety Communication – Proton Pump Inhibitors and Fracture Risk National Institute on Aging (NIA) – Medication Use in Older Adults ⚖️ MEDICAL DISCLAIMER This content is for educational purposes only and is not intended as medical advice. Always consult a licensed healthcare professional before starting, stopping, or changing any medication. Never discontinue prescribed medications without medical supervision.