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Ionis’ Program Update of ION582 for Individuals Living with Angelman Syndrome Rebecca Crean, PhD Ionis For more information, visit https://cureangelman.org Recorded November 9th, 2024 in Orlando, Florida Disclaimer: The information contained in these slides is provided for informational purposes only and should not be construed as medical, legal, financial, or any other type of professional advice. The views and opinions expressed in this presentation and on the following slides are solely those of the presenter and not necessarily those of FAST. FAST does not guarantee the accuracy or reliability of the information provided herein. Under no circumstances, including negligence, shall FAST or its officers, directors, employees, partners, or licensors be liable for any direct, indirect, incidental, special, punitive, or consequential damages that may result from the access of, or use, or inability to use content from this presentation. Unauthorized modification, reproduction, translation, or distribution of any part of these slides is strictly prohibited.