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Brain Aging and Mental Health

Main Chapters: 00:00 Intro – Brain Aging and Mental Health 00:12 Take home message 01:28 What is Aging? 03:26 Difficulties with Researching Aging 06:59 Aging and Brain Changes 10:17 Study on Aging and Brain Changes 13:17 Brain Aging and ADHD 16:01 Conclusion If we live long enough, our brains age. But differentiating normal aging from dementia, or from ongoing ADHD, can be particularly tricky. Some aging experts consider all decreases in efficiency or functioning as signs of pathology.  Both physical changes (shrinkage of both gray and white matter, alteration in patterns of brain activation) and functional (slower mental processing, memory changes) occur with aging.  In general, crystalized intelligence  - fixed knowledge like vocabulary, what objects are and how to use them, declines less than does fluid intelligence (flexibility of thought, working memory).   ----- Follow   / dockruse   on Medium for hundreds of full length articles on this subject and more! Access to Full Medium articles requires paid membership. ----- References: Topological turning points across the human lifespan (2025) https://www.nature.com/articles/s4146... The effects of computerized executive function training on the youth with ADHD: A systematic review and meta-analysis (2026) https://www.sciencedirect.com/science... Cognitive Profile of ADHD in Older Adults: A Systematic Review (2025) https://pmc.ncbi.nlm.nih.gov/articles... The Aging Brain and Executive Functions Revisited: Implications from Meta-analytic and Functional-Connectivity Evidence (2021) https://pmc.ncbi.nlm.nih.gov/articles... Normal Cognitive Aging (2013) https://pmc.ncbi.nlm.nih.gov/articles... Full Chapter list: 00:00 Intro – Brain Aging and Mental Health 00:12 Take home message 01:28 What is Aging? 02:18 Comparing Healthy Brains to Brains with Conditions 03:26 Difficulties with Researching Aging 04:27 Cross-sectional Studies 05:51 Longitudinal Studies 06:59 Aging and Brain Changes 08:27 Fluid (gf) and Crystallized (gc) Intelligence 09:19 Memory and Executive Functions 10:17 Study on Aging and Brain Changes 11:12 Brain Changes During Childhood and Adolescence 12:08 Brain Changes During Adulthood 12:39 Brain Changes During Early and Late Aging 13:17 Brain Aging and ADHD 13:39 Brain Aging and Inattentive ADHD Symptoms 14:27 Brain Aging and Hyperactive / Impulsive ADHD Symptoms 14:52 Brains with ADHD and Aging 16:01 Conclusion 17:35 Outro ------------------------- Psychiatrist, neuroscientist, and author John Kruse, MD, PhD presents practical, actionable, well-researched information about treatment options that scientists and clinicians recommend for adult ADHD and other mental health conditions. Subscribe if you're curious about how neuroatypical brains can optimize their functioning in our shared, and somewhat strange, world. ADHD topics have a pink background, and those on more general mental health topics have a purple background. A small collection of Politics related videos have an orange background. Dr. Kruse has posted videos in the "Videos", "Live", and "Shorts", sections of this channel. You're welcome to email him with topics you want discussed or people you think he should interview. [email protected] #health #mentalhealth #aging #brain #adhd