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What LSD Does to Your Brain

What does LSD actually do to your brain? This video explains, in clear and simple terms, how LSD interacts with the brain’s perception systems, why it changes the way reality is processed, and how it temporarily alters meaning, identity, and sensory filtering. Rather than focusing on experiences or sensational stories, this explainer looks at the neuroscience behind LSD — how it affects serotonin signaling, brain connectivity, perception, and the sense of self. We explore why LSD is powerful in tiny amounts, how it loosens the brain’s predictive filters, why outcomes can be unpredictable, and what happens as the brain returns to baseline. This video is grounded in established neuroscience and designed for a general audience. No medical background is required. Complex ideas are explained using simple examples, clear language, and a calm, non-judgmental tone. If you’ve ever wondered how perception is constructed inside the brain — and how easily it can be altered — this video offers a science-based explanation without hype, fear, or glorification. • National Institute on Drug Abuse (NIDA) — LSD and psychedelic neuroscience • National Institutes of Health (NIH) — Serotonin receptors and perception • Neuroscience and Behavioral Reviews — 5-HT2A receptors and altered cognition • Nature Neuroscience — Brain connectivity and psychedelics • Johns Hopkins University — Psychedelic research and brain networks • Harvard Medical School — Predictive processing and perception • Frontiers in Human Neuroscience — Default mode network and identity If this video helped replace myths with understanding, consider sharing it with someone who values accurate information over exaggeration. And if you want more calm, science-based explainers about how the brain really works, subscribe to the channel. Understanding isn’t endorsement — it’s safety, clarity, and knowledge.