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I eliminated all hypertension medications in 14 months. My blood pressure dropped from 148/92 on three medications to 118/74 with zero medications—and it's stayed normal for over two years. I'm Dr. Walter Miles, professor of genetics and metabolic biology, and I achieved this by targeting four cellular mechanisms that standard blood pressure treatment completely ignores. Your doctor tells you hypertension is about pressure—too much force against arterial walls. The solution? Medication to lower those numbers. But here's what they don't tell you: pills manage symptoms while your vessels continue deteriorating. The medication masks the disease without healing it. Hypertension isn't a pressure problem—it's a structural vascular problem occurring at the microscopic level. Four specific mechanisms drive it: MECHANISM #1: Your endothelial glycocalyx—the protective coating inside your arteries—becomes degraded by hyperglycemia and oxidative stress. Once damaged, inflammation begins, nitric oxide production fails, and blood pressure rises. I restored mine with 1,000mg fucoidan daily, strict glucose control below 140 mg/dL, and high-polyphenol foods providing 1,500mg daily. MECHANISM #2: Your arteries calcify when Matrix Gla Protein (MGP) remains inactive due to vitamin K2 deficiency. This makes vessels rigid, driving systolic hypertension. I reversed arterial stiffness with 360μg vitamin K2 (MK-7), 5,000 IU vitamin D3, and 600mg magnesium glycinate daily. My pulse wave velocity dropped 21% in 12 months. MECHANISM #3: Your endothelial cells stop producing nitric oxide when eNOS becomes uncoupled. I restored NO production with 500mg dietary nitrate from arugula and beets, isometric handgrip training (proven to lower BP by 11 mmHg), and exclusive nasal breathing. MECHANISM #4: Elevated insulin locks your kidneys in sodium retention mode regardless of salt intake. I normalized insulin from 16 to 7 μIU/mL through 16:8 time-restricted feeding, resistance training 3x weekly, and apple cider vinegar before meals. After 14 months implementing all four mechanisms, I eliminated lisinopril, amlodipine, and hydrochlorothiazide completely. My blood pressure remains 116/72 with no medications. My flow-mediated dilation improved 133%. My arterial stiffness decreased 21%. These are structural changes measured by imaging and biomarkers. This isn't symptom management—this is vascular regeneration. The research exists in peer-reviewed journals. The mechanisms are proven. Your vessels can heal when you address the causes rather than masking the numbers. Dr. Walter Miles Professor of Genetics and Metabolic Biology