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Is your patient truly allergic to penicillin, or is there something else going on? An allergy to penicillin is a serious condition, as it severely limits the choice of antibiotics for various diseases. The most widely used antibiotics are penicillins or those that share a similar structure with penicillins, such as cephalosporins and carbapenems. This is why it is so important to determine whether your patient is really allergic to penicillin and what that allergic reaction looks like. This video will teach you the key questions you need to ask to find out. If you find this content helpful and want a structured way to approach antibiotics and infectious diseases, take a look at my membership. Inside, you’ll find full lectures, practical cheat sheets, and a clear clinical reasoning framework you can rely on in daily practice. You can explore everything at your own pace, and you can cancel anytime. Learn more here: https://drviktorkotarski.podia.com/ DISCLAIMER: These examples of clinical cases are fictional but made to resemble real-life scenarios that doctors are likely to encounter in clinical practice. These are educational videos for medical professionals and students. They are NOT intended to supplant clinician judgment and they are certainly NOT medical advice! I do NOT practice medicine over the Internet. If you have concerns or questions about your health, please talk to your doctor. CHAPTERS: 00:00 Patient claims to be allergic to penicillin 01:23 What to ask a patient who is supposedly allergic to penicillin 01:41 Type 1 hypersensitivity (IgE-mediated hypersensitivity reactions) 02:02 Delayed hypersensitivity reactions (Stevens-Johnson syndrome, TEN, DRESS, serum sickness) 02:52 Allergic reaction to penicillin in childhood