The Long Hangover Adolescent Intermittent Ethanol's Effects on Hippocampal Neuroimmune and... скачать в хорошем качестве

The Long Hangover Adolescent Intermittent Ethanol's Effects on Hippocampal Neuroimmune and...

Presented By: Kati Healey, MA, PhD Speaker Biography: My scientific focus overall is aimed at understanding the persistent behavioral, cellular, and molecular substrates of drug addiction. My current research investigates the effects of adolescent intermittent ethanol on adult memory and reward system neurobiochemistry and behavior. I received my BS in Psychology with minors in Chemistry and Biology from the University of Pittsburgh and my MA and PhD in Behavioral and Integrative Neuroscience at the University of North Carolina at Chapel Hill. Webinar: The Long Hangover: Adolescent Intermittent Ethanol's Effects on Hippocampal Neuroimmune and Cell Death Markers, Reversal by Donepezil Webinar Abstract: Adolescence is a critical period for the developing brain, and binge drinking during this neuromaturation can result in enduring abnormal brain function and behavior. Repeated adolescent binge ethanol drinking is associated with increased risk of alcohol use disorders, psychopathology, and cognitive dysfunction in adulthood. In rodents, adolescent intermittent ethanol (AIE) exposure causes diminished adult hippocampal neurogenesis and dendritic spine density in the hippocampal dentate gyrus. Donepezil (Aricept), an anti-cholinesterase with microglial inhibitory actions, has been shown to reverse the effect of AIE on dendritic spine density. Therefore, we hypothesized donepezil would reverse the AIE-induced decrease of dentate neurogenesis as well as AIE-induced neuroimmune and epigenetic changes that may underlie it. Earn PACE Credits: 1. Make sure you’re a registered member of LabRoots https://www.labroots.com/virtual-even... 2. Watch the webinar on YouTube or on the LabRoots Website https://www.labroots.com/webinar/hang... 3. Click Here to get your PACE credits (Expiration date – August 25, 2023): https://www.labroots.com/credit/pace-... LabRoots on Social: Facebook:   / labrootsinc   Twitter:   / labroots   LinkedIn:   / labroots   Instagram:   / labrootsinc   Pinterest:   / labroots   SnapChat: labroots_inc