Is the Stille Reaction Useful? скачать в хорошем качестве

Is the Stille Reaction Useful?

Want to learn more about drug discovery? https://www.simplydrugdiscovery.com/s... In this video, I discuss palladium-catalysed cross couplings, a key reaction in organic synthesis. This reaction is commonly used in medicinal chemistry and drug discovery to develop and produce new pharmaceuticals. I also about the discovery and history of the Stille coupling, and how it can help overcome some of the problems associated with the Suzuki reaction. References: Cross couplings in Drug discovery https://www.mdpi.com/1420-3049/25/15/... Eaborn Work: https://www.sciencedirect.com/science... Migita Work: https://academic.oup.com/chemlett/art... https://www.sciencedirect.com/science... Stille work: https://pubs.acs.org/doi/abs/10.1021/... https://pubs.acs.org/doi/abs/10.1021/... https://pubs.acs.org/doi/abs/10.1021/... https://onlinelibrary.wiley.com/doi/1... Stille Review: https://pubs.acs.org/doi/epdf/10.1021... In memory of Stille: https://pubs.acs.org/doi/10.1021/ma00... Suzuki: https://www.tandfonline.com/doi/abs/1... Suzuki review: [https://www.sciencedirect.com/science... Suzuki reaction.-,The products of the Suzuki coupling reaction show significant advantages,lapatinib%2C atazanavir%2C and clonazepam](https://www.sciencedirect.com/science.... Derke Lowe https://www.science.org/content/blog-... 2-pyridyl problem: https://onlinelibrary.wiley.com/doi/1... Protodeboronation: https://pubs.acs.org/doi/10.1021/jacs... https://pubs.acs.org/doi/10.1021/jo50... Synthetic Methods in Drug Discovery: https://books.rsc.org/books/edited-vo... Patents: https://patentscope.wipo.int/search/e... https://patentscope.wipo.int/search/e... VEGFR https://pubs.acs.org/doi/10.1021/op03... Attributions: 2010 Nobel Prize:https://en.m.wikipedia.org/wiki/File:... Suzuki:https://en.wikipedia.org/wiki/File:No... Eaborn photo:https://pubs.rsc.org/en/content/artic... https://commons.wikimedia.org/wiki/Fi... Biotage: https://www.biotage.com/large-scale-p... Merck logo:https://commons.wikimedia.org/wiki/Fi...