Cell based Assay to Detect Antibodies in Enzyme Replacement Therapies | Protocol Preview скачать в хорошем качестве

Cell based Assay to Detect Antibodies in Enzyme Replacement Therapies | Protocol Preview

Watch the Full Video at https://www.jove.com/v/57777/detectio.... Detection of Antibodies That Neutralize the Cellular Uptake of Enzyme Replacement Therapies with a Cell-based Assay - a 2 minute Preview of the Experimental Protocol Ruby Cheung, Gregory W. deHart, Lynne Jesaitis, Stephen J. Zoog, Andrew C. Melton BioMarin Pharmaceutical Inc,; Here we present a cell-based flow cytometry method to detect neutralizing antibodies or other factors that interfere with the cellular uptake of enzyme replacement therapies in a human matrix, such as cerebral spinal fluid (CSF) or human serum. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel:    / jovejournalofvisualizedexperiments