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“We’re Upgrading Humanity” #wait. Sources- PMID 38424184 CBS News Preimplantation Genetic Testing for Monogenic disorders (PGT-M), formerly known as PGD, is a sophisticated reproductive technology used alongside In Vitro Fertilization (IVF) to screen embryos for specific inherited conditions before they are transferred to the uterus. By biopsying a few cells from a five-day-old embryo (blastocyst), scientists can identify the presence of devastating life-altering conditions, such as cystic fibrosis, Huntington’s disease, or Tay-Sachs. For families with a known history of these genetic disorders, this technology provides a vital pathway to prevent the transmission of profound suffering and early mortality, offering parents the peace of mind that their child will not inherit a specific, life-limiting mutation. As our ability to map the human genome grows, the conversation has shifted toward the ethical boundaries of "polygenic" screening. Unlike single-gene disorders, traits like intelligence (IQ) and height are governed by thousands of genetic variants, each having a miniscule effect. There is significant concern regarding the "designer baby" phenomenon, where the technology could be abused to select embryos based on these complex polygenic scores. Beyond the questionable accuracy of such predictions, the ethical risks are immense: it could exacerbate social inequalities, reduce human genetic diversity, and treat children as "products" designed to meet parental specifications. Maintaining the focus on preventing severe medical illness is essential to ensure that this medical breakthrough remains a tool for health rather than an instrument of eugenics. #ivf #fertility #parents