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Ever notice how some people eat whatever they want and never gain weight, while you track every calorie and still struggle? You're not doing it wrong. Your biology is just different. In this video, Dr. Siddhant Shukla, Founder & CEO of Renewist, breaks down the real science behind why fat loss is harder for some people and what you can actually do about it. 🔬 WHAT WE COVER: Why genetics give some people a metabolic head start How insulin sensitivity determines where your carbs go — muscle or fat The role of your gut microbiome in fat storage and hunger How chronic stress and cortisol keep you holding onto belly fat Why poor sleep sabotages your hunger hormones every single day NEAT — the hidden 300–500 calorie difference most people never consider Metabolic adaptation: why cutting calories doesn't work the same for everyone How to work WITH your biology to optimize fat loss ⏰ TIMESTAMPS: 0:00 — Why some people stay lean effortlessly 0:20 — Genetics & metabolism 0:45 — Insulin sensitivity explained 1:10 — Gut health & your microbiome 1:35 — Cortisol, stress & belly fat 2:00 — Sleep hormones: leptin & ghrelin 2:25 — What is NEAT? 2:50 — Muscle mass & calorie burning 3:15 — Metabolic adaptation 3:45 — How to optimize your unique biology 4:10 — Personalized fat loss with Renewist 💡 THE KEY TAKEAWAY: Fat loss isn't just about eating less and moving more. It's about understanding your unique metabolic blueprint, and building a strategy designed specifically for your body, your hormones, and your lifestyle. 📩 READY FOR A PERSONALIZED FAT LOSS STRATEGY? Book your consultation with Dr. Siddhant Shukla at Renewist: 👉 renewist.com 🔔 Subscribe for honest, science-based health and longevity content, no fads, no filters, just facts. 💬 Drop a comment: Which of these factors surprised you the most? 👍 If this helped you stop comparing yourself to others, share it with someone who needs to hear it. DISCLAIMER: This video is for educational purposes only and does not constitute medical advice. Please consult a qualified healthcare professional before making changes to your diet, exercise, or health routine. #FatLoss #MetabolismExplained #WeightLossScience #InsulinResistance #GutHealth #StressAndWeight #SleepAndWeight #NEAT #MetabolicHealth #Renewist #DrSiddhantShukla #PersonalizedHealth #HormoneBalance #ScienceBasedFitness #Longevity