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1.Nasal polyposis with associated sinus opacities Maxillary, frontal and sphenoidal sinus opacities are very fre¬quent on CT scans in nasal polyposis, varying in presentation from sinus to sinus and patient to patient. They indicate associated paranasal sinus pathology: • opacity suggesting a simple serous sinus cyst need not have any impact on how polyposis is managed; • in case of opacity suggesting mucosal hypertrophy not likely to hinder NO production, ostial function should be preserved; • opacity suggesting secretion retention may be an indication for aspiration-drainage through the natural ostium, to determine the type of secretion: seromucous, purulent, or sometimes firm and adhesive, requiring endoscopic sinusotomy for evacuation; • when sinus opacity is complete, this does not in itself determine its nature; • associated opacity suggestive of a sinus fungus ball may be an indication for surgery. 2.Nasal polyposis associated with olfactory groove hamartoma Respiratory epithelial adenomatoid hamartoma (REAH) [28] should be suspected in case of opacification and enlargement of the olfactory grooves on CT . Not all olfactory groove polyps are REAHs, and only histology can confirm diagnosis if suspect polyps are identified for pathologic analysis 3.Unilateral nasal polyposis Unilateral nasal polyposis with healthy contralateral ethmoid on CT represents, if not proven otherwise, a tumor masked by sen¬tinel edematous polyps. Unilateral nasal polyposis, of whatever stage, with pathological contralateral ethmoid on CT may represent an asymmetric polypo¬sis 4.Childhood idiopathic nasal polyposis Nasal polyposis is usually diagnosed in adulthood. In case of diagnosis before the age of 18 years, cystic fibrosis, primary ciliary dyskinesia syndrome and immune deficiency should be screened for systematically. If etiological work-up is negative, childhood idiopathic nasal polyposis can be diagnosed, with treatment as in adults 5.Non-allergic rhinitis with eosinophilia syndrome