Using Moran's I to identify spatially variable genes in spatial transcriptomics data скачать в хорошем качестве

Using Moran's I to identify spatially variable genes in spatial transcriptomics data

In this lecture, we will learn how to analyze spatial transcriptomics data to distinguish spatially variable genes that exhibit coordinated spatial variation, from genes that may be highly variable but in a less spatially coordinated manner using the Moran's I statistic. Key moments: Main Lecture on Moran's I as applied to spatial transcriptomics data:    • Using Moran's I to identify spatially vari...   Practice:    • Using Moran's I to identify spatially vari...   Evaluating the statistical significance of Moran's I under spatial randomness null model:    • Using Moran's I to identify spatially vari...   Coding demo using MERINGUE to apply Moran's I:    • Using Moran's I to identify spatially vari...   Alternative ways of encoding adjacency relationships:    • Using Moran's I to identify spatially vari...   Additional relevant coding tutorials and resources: Additional packages for running Moran's I in R: https://jef.works/blog/2024/08/29/the... Combining MERINGUE with SEraster for faster analysis of spatially variable genes: https://jef.works/blog/2024/03/24/spa... MERINGUE paper: https://jef.works/assets/papers/Mille... MERINGUE website with additional tutorials: https://jef.works/MERINGUE/ Music by Christoph Scholl: https://pixabay.com/users/tuesdaynigh...