Renal Hemodynamics & GFR | Pharmacotherapeutics | SNS Institution скачать в хорошем качестве

Renal Hemodynamics & GFR | Pharmacotherapeutics | SNS Institution

#snsinstitutions #snsdesignthinkers #designthinking #snscphs #drkkclinipharm #snsdrdkrishnakumar #clinirxmed #Kidney #RenalPhysiology #Nephron #UrineFormation #HumanPhysiology #MedicalEducation #NursingEducation #AlliedHealthSciences #AnatomyAndPhysiology #PhysiologyLecture #MedicalStudents #RenalSystem Understanding the "Delicate Balance" of the kidney is essential for any medical or pharmacy professional. In this video, we delve into the core mechanisms of renal physiology, from the precise vascular pathways of blood to the complex hormonal systems that maintain homeostasis. • The Renal Vascular Path: Follow the journey of blood from the Renal Artery through the segmental and interlobar branches to the critical filtration units. • The Glomerular Sieve: An in-depth look at the three-layer barrier (Endothelium, Basement Membrane, and Podocytes) that acts as a highly selective filter. • Glomerular Dynamics: We break down the "tug-of-war" between hydrostatic and oncotic pressures that determines your Glomerular Filtration Rate. • Autoregulation Mechanisms: How the kidneys use the Myogenic Mechanism and Tubuloglomerular Feedback to maintain a steady state despite changes in blood pressure. • The RAAS System: A multi-system breakdown of how Angiotensin II orchestrates systemic vasoconstriction, thirst, and electrolyte reabsorption. • Clinical Applications: Interpreting the effects of common medications like NSAIDs and ACE Inhibitors on renal perfusion, and why dose adjustments are critical in renal impairment. Key Concepts Covered: • Renal Blood Flow vs. Renal Plasma Flow. • Filtration Fraction and its role in proximal tubule reabsorption. • Pathophysiology of Systolic Heart Failure and Nephrotic Syndrome