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Creatine is one of the most researched molecules in human biology — yet it remains one of the most misunderstood. In this in-depth 21-minute episode, Dr. David Sinclair breaks down exactly what creatine does inside the human body, far beyond muscle building and gym performance. You’ll learn how creatine works at the cellular level to support ATP energy production, muscle strength, brain function, and metabolic health. This video explains why creatine is not a steroid, not a hormone, and not just for athletes — but a naturally occurring compound essential for energy resilience, especially as we age. Dr. Sinclair explores how creatine supports mitochondrial function, protects against age-related muscle loss, enhances cognitive performance under stress, and why creatine levels decline with age. We also address common myths about kidney damage, water retention, and long-term safety using real scientific evidence. If you’re over 30, focused on longevity, or interested in optimizing strength, brain health, and cellular energy, this video will completely change how you think about creatine. This is not hype. This is biology, explained simply. ⏱️ Time Stamps: 00:00 – Why Creatine Is Massively Misunderstood 01:48 – What Creatine Actually Is (Not a Supplement Myth) 04:12 – ATP, Cellular Energy, and How Creatine Works 06:35 – Creatine’s Role in Muscle Strength & Power 09:02 – Creatine and Aging: What Changes After 30 11:18 – Brain Energy, Focus, and Mental Fatigue 13:42 – Creatine Safety, Kidneys, and Long-Term Use 16:07 – Creatine for Longevity & Metabolic Health 18:39 – Who Should Take Creatine (And Who Shouldn’t) 20:12 – Final Thoughts: Creatine as a Longevity Tool 🏷️ SEO Tags: creatine, what does creatine do, creatine explained, dr david sinclair creatine, creatine benefits, creatine for aging, creatine longevity, creatine muscle growth, creatine brain health, creatine mitochondria, creatine energy, creatine ATP, is creatine safe, creatine kidney myth, creatine over 40, creatine for men, creatine for women, creatine supplement science, creatine monohydrate, creatine dosage, creatine research, creatine and muscle loss, creatine metabolism, creatine nutrition, creatine health benefits, anti aging supplements, longevity supplements, muscle health aging, mitochondrial health, cellular energy, 🔑Keywords: what does creatine do in the body, creatine benefits for aging, creatine for longevity science, creatine explained simply, creatine for brain health, creatine ATP energy, creatine muscle and strength, creatine for older adults, creatine mitochondrial function, creatine and sarcopenia, creatine daily use, creatine long term safety, creatine metabolism explained, creatine supplement facts, creatine research studies, creatine and cognitive function, creatine over 40 benefits, creatine and insulin sensitivity, creatine for men over 50, creatine for women health, creatine and aging muscles, creatine for recovery, creatine performance science, creatine nutrition guide, creatine health myths, creatine anti aging, creatine and lifespan, creatine cellular energy, creatine vs protein, creatine science explained, 🔥 Hashtags: #Creatine, #CreatineExplained, #DrDavidSinclair, #Longevity, #AntiAging, #MuscleHealth, #BrainHealth, #CellularEnergy, #ATP, #Mitochondria, #HealthyAging, #CreatineBenefits, #CreatineScience, #NutritionScience, #Biohacking, #HealthOptimization, #StrengthTraining, #MuscleLoss, #Sarcopenia, #Over40Health, #FitnessScience, #SupplementScience, #LongevityScience, #AgingWell, #HumanBiology, #MetabolicHealth, #CreatineMyths, #HealthEducation, #Wellness, #LifeSpan,