Synthesis Workshop: Electron-primed Photoredox Catalysis with Alyah Chmiel (Episode 69) скачать в хорошем качестве

Synthesis Workshop: Electron-primed Photoredox Catalysis with Alyah Chmiel (Episode 69)

In this Research Spotlight episode, we're joined by Alyah Chmiel (Wickens lab, UW Madison), who shares with us her work on using electron-primed photoredox catalysis to carry out reductions. Key reference: J. Am. Chem. Soc. 2021, 143, 10882–10889 https://doi.org/10.1021/jacs.1c05988 Other references (in order of appearance): J. Am. Chem. Soc. 2020, 142, 2093–2099 J. Am. Chem. Soc. 2021, 143, 4125–4132 Angew. Chem. Int. Ed. 2021, 60, 21418– 21425 J. Am. Chem. Soc. 2021, 143, 10882–10889 J. Am. Chem. Soc. 2021, 143, 10882-10889 Nature 2021, 596, 74–79 [See Episode #66] For pioneering work from König on reductive catalyst activation, see: Science, 2014, 363, 725-728 J. Am. Chem. Soc. 2020, 142, 2093–2099 Commercial aryl halide numbers were compiled by Weix & co-workers; see: J. Am. Chem. Soc. 2019, 141, 10978–10983 For a review on aryl radical reactivity, see: Chem. Rev. 1988, 88, 765–792 For recent work on C(sp2)–O and C(sp2)–N cleavage, see: (a) J. Am. Chem. Soc. 2020, 142, 1603–1613; (b) Chem 2021, 7, 1653–1665 For a review on amine radical cations in photoredox catalysis, see: Beilstein J. Org. Chem. 2013, 9, 1977–2001 For related work accessing CO2• – from formate via HAT, see: Hendy, C. M.; Smith, G. C.; Xu, Z.; Lian, T.; Jui, N. T. J. Am. Chem. Soc. 2021, 143, 8997–8992 Developing new potent photooxidants: J. Am. Chem. Soc. 2021, 143, 4125–4132 Exploiting formate salts as C1 sources: J. Am. Chem. Soc. 2021, 143, 13022-13028