Quorum Sensing In Bacteria In Urdu | How Bacteria Talk To Each Other In Hindi || QS In V. Fischeri скачать в хорошем качестве

Quorum Sensing In Bacteria In Urdu | How Bacteria Talk To Each Other In Hindi || QS In V. Fischeri

How Bacteria Talk To Each Other In Details In Urdu Hindi #Quorum Sensing In Living Torch #Quorum Sensing In P. Aeruginosa #Quorum Sensing In Fibrio Fischeri #Quorum Sensing In Gram Negative Bcateria #Quorum Sensing In Gram Positive Bacteria ........................................................................................................................................................... Quorum sensing is the regulation of gene expression in response to fluctuations in cell-population density. Quorum sensing bacteria produce and release chemical signal molecules called autoinducers that increase in concentration as a function of cell density. QS is the mechanism whereby an individual bacterium produces small diffusible molecules that can be detected by surrounding organisms. In P. aeruginosa, and most Gram-negative bacteria, these signal molecules are acyl homoserine lactones (AHLs). Based on the facts that QS regulates such an array of P. aeruginosa factors and that deletion of QS regulators attenuates P. aeruginosa virulence, it is conceivable that QS would be an ideal target for the inhibition of Pseudomonas infections. Multidrug-resistant P. aeruginosa are becoming more prevalent, and current antimicrobial treatments for cystic fibrosis are unable to eradicate P. aeruginosa infections. Therefore, alternative mechanisms for targeting P. aeruginosa have been the focus of much research. Therapeutics that target and inhibit QS in P. aeruginosa would attenuate the virulence of the bacterium and thus potentially assist the host immune response in clearing the infection. Several components of the QS networks represent ideal targets for potential therapeutics: (a) LasR and RhlR activation (b) AHL formation and activity, and (c) lasR/lasI and rhlR/rhlI expression. Quorum sensing allows individual bacteria within colonies to coordinate and carry out colony-wide functions such as: sporulation, bioluminescence, virulence, conjugation, competence and biofilm formation. ............................................................................................................................................................