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Inaugural Lecture - At Microsecond-Scale, Inside a Datacenter, by Prof. Edouard Bugnion Abstract Our cell phones are the defining, visible innovation of our era, yet datacenters form the invisible part of that digital iceberg. Within a datacenter, thousands or more machines communicate through very short remote procedure calls that often take a few microseconds to service but must, nevertheless, meet tight service-level objectives expressed in terms of tail latency. At such microsecond-scale, operating systems and network overheads dominate and limit overall system efficiency. I will present key results from the EPFL Datacenter Systems Laboratory that (1) leverage virtualization hardware for energy proportionality and tail-tolerance, (2) innovate at the network protocol layer to eliminate head-of-line blocking and offer load balancing and consensus within the transport. About the speaker Prof. Edouard Bugnion joined EPFL in 2012, with a teaching and research focus on datacenter systems. Before joining EPFL, he spent 18 years in the US, where he received his PhD from Stanford, and co-founded two startups: VMware and Nuova Systems (acquired by Cisco). He served as VMware’s first CTO and was later the VP/CTO of Cisco’s Server, Access, and Virtualization Technology Group. At EPFL, he is the Academic Co-director of the Swiss Data Science Center, he has served as the Vice-President for Information Systems (2017-20) as well as on the COVID-19 Independent Scientific Task Force for the Swiss Confederation (2020-22). Prof. Bugnion is an ACM Fellow and a member of the Swiss Academy of Technical Sciences (SATW). He received the SIGOPS Hall of Fame Award for Disco, the ACM Systems Award for VMware, and Best Paper Awards at SOSP, OSDI and Eurosys.