A Conversation with an MPN Specialist: What You Should Know About Your Bloodwork скачать в хорошем качестве

A Conversation with an MPN Specialist: What You Should Know About Your Bloodwork

MPN Advocacy & Education International spoke with Dr. Raajit Rampal, Memorial Sloan Kettering, to discuss the important factors in your blood work and answer patient questions. TIMESTAMPS 00:00 What You Should Know About Your Bloodwork 00:56 What does the blood work look like in the lab? 10:38 What are the different mutations associated with polycythemia vera? 12:38 What are immature granulocytes and what does it mean if they are high? 13:35 Why does my portal vein stent continue to get blocked? 15:25 What is the significance of allele burden? Does it signal disease progression? 20:05 What medication can I take other than Ojjaara? 21:37 What cells are the first to exhibit progression from PV to MF or AML? 23:55 I was taken off BESREMi and then went back to it. Now I am incredibly itchy. Is this an allergic reaction? 26:15 Are there any combination clinical trials with interferon and ruxolitinib? 27:22 What is the difference between bone pain and regular pain? 29:14 Can I lower my hydroxyurea dosage if I am feeling good and have control over my numbers? 30:51 Can interferon heal or slow progression to myelofibrosis? 34:02 Can you talk about ocular migraines in PV? 37:07 If the mutation can be minimized, what is preventing it from being eliminated? 37:51 What would cause my WBC and NA to jump over the past few months? 38:42 When do you start to treat your patients? 41:54 What is your experience with an MF patient with indolent disease who is no longer proliferative? 43:15 Do you have any ET patients with JAK2 mutation that now have a CALR mutation? 44:28 Should a PV patient in their mid 70s switch from HU to BESREMi to increase longevity? 45:36 Is it common for WBC counts to normalize on BESREMIi? 46:21 How will the federal cuts affect upcoming research and funding? 49:12 Is the SHB23 mutation an indication of poor prognosis and disease progression? 50:17 Are ET patients on hydroxyurea and aspirin more prone to nosebleeds and slower healing? 51:16 How many people in the US have an MPN? 53:10 How low is too low for your hematocrit reading as a PV patient? 54:42 Is it common for an MPN patient to have elevated liver enzymes? 56:02 At what point do you recommend a stem cell transplant to your patients? 58:38 Can a person have ET and PV? 59:06 What should a hematologist be looking at in more rural areas, and what questions should I be asking?