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If you’re entering perimenopause and suddenly noticing more abdominal fat, higher cholesterol, poorer sleep or increased anxiety, you’re not imagining it. In this episode, I’m joined by Professor Sarah Berry to unpack what actually changes in women’s cardiometabolic health during the menopause transition. We explore why premenopausal women are often metabolically protected compared to men, what shifts during perimenopause, and how declining estrogen impacts fat distribution, blood glucose control, inflammation and cholesterol. WHAT YOU WILL LEARN • Why cardiometabolic health often worsens during perimenopause • When visceral fat redistribution typically begins • The role of estrogen in fat storage, cholesterol and inflammation • Whether hormone therapy protects against abdominal fat gain • Why postmenopausal women experience larger blood sugar spikes from the same meal • How glucose dips can drive an extra 300+ calories per day • What ApoB really means and why it matters beyond LDL • The truth about seed oils, saturated fat and cardiovascular risk • Why soy isoflavones work for some women but not others • How fiber diversity and polyphenols shape the microbiome • Why eating speed and late-night eating impact metabolic health • The power of consistent sleep and eating rhythms • How replacing typical snacks with almonds predicted a 30% drop in cardiovascular risk TIMESTAMPS: 00:00 Intro: Why Cardiometabolic Risk Increases During Perimenopause 05:01 Does Hormone Therapy Protect Against Visceral Fat & Cholesterol Changes? 08:00 Do Soy Isoflavones Help Menopause Symptoms? The Gut Microbiome Factor 13:42 How to Improve Your Gut Microbiome through Diet 19:01 Why Belly Fat Increases in Perimenopause (Estrogen, Hunger & Blood Sugar) 27:39 Saturated Fat Explained: Butter vs Yogurt & The Food Matrix 31:51 Do Seed Oils Cause Inflammation? The Scientific Evidence 39:25 What Is ApoB? The Cholesterol Marker Linked to Heart Disease 45:31 Eating Speed, Late-Night Meals & Metabolic Health in Midlife 50:42 Almonds vs Processed Snacks: The Study Predicting 30% Lower Heart Risk VALUABLE RESOURCES • Take the BioSyncing Quiz to help you understand what’s actually happening in your body — and how to fix it. 👉 https://biosyncing.scoreapp.com/ A BIG thank you to our sponsors who make the show possible: • Stride - Find out your biological age and how your daily habits are influencing it with DNA, bloodwork and microbiome testing with a Stride One membership 👉 https://www.getstride.com/angela/ for 10% off ABOUT THE GUEST Professor Sarah Berry is a Professor of Nutritional Sciences at King’s College London and Chief Scientist at ZOE. She leads large-scale research on personalised nutrition, metabolic health and how individuals respond differently to food, including the global PREDICT studies. With over two decades of research experience and more than 35 human nutrition trials, her work focuses on cardiometabolic health, menopause, the microbiome and precision nutrition. Instagram: / drsarahberry X: https://x.com/saraheeberry Want to go deeper? Start here: 💌 Fresh Start Mondays Newsletter Your weekly 3-minute guide to creating the healthiest, most vibrant version of you. Each Monday, get one simple habit to boost energy, balance hormones, and enhance longevity - joined by 25,000+ women worldwide. 👉 https://angelafosterperformance.com/ 🌸 Live Younger Collective Your future of feminine longevity starts here. Join the brand-new membership for soul-driven women in midlife who are ready to enhance their lifespan and healthspan by syncing their hormones, biology, and lifestyle with intention. 👉 https://academy.angelafosterperforman... 🥗The Ultimate Guide to Creatine for Women - 👉 https://academy.angelafosterperforman... ⚡️ 10 Habits that Helped me reverse my Biological Age by 25 years in Perimenopause - 👉 https://academy.angelafosterperforman... 👩💼 About Me: I’m Angela Foster - Nutritionist, Health & Performance Coach, and host of the High Performance Health podcast. After leaving my career as a corporate lawyer due to burnout and illness, I rebuilt my physical, mental, and spiritual health through integrative science and lifestyle practices. Now, I help women in midlife feel 10 years younger by syncing with their biology, not fighting against it. Through my Live Younger Collective and podcast, I share evidence-based strategies to enhance energy, balance hormones, and extend your healthspan. Follow me for daily health and performance tips: Instagram: @angelasfoster Facebook: @AngelaFosterPerformance #angelaFoster #HighPerformanceHealth #WomensHealth #Longevity